Vascular Inflammation and Metabolism Laboratory
University of Ottawa Heart Institute
Who We Are
Vascular Inflammation and Metabolism Laboratory |
The Vascular Inflammation and Metabolism Laboratory studies how microRNAs alter the expression of key genes involved in the pathogenesis of atherosclerosis and other chronic inflammatory diseases, such as type II diabetes. The team also studies novel mechanisms of inflammation that promote plaque vulnerability. We employ animal models of human disease, in vitro assays of inflammation, cholesterol homeostasis and cellular activation, and analyze pathways of interest in human plasma and atherosclerotic plaque samples.
The laboratory is funded by the Canadian Institutes of Health Research (CIHR), the Heart and Stroke Foundation of Canada (HSF) and the European Research Area Network on Cardiovascular Diseases (ERA-CVD).
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our Fearless Leader |
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Katey RaynerKatey Rayner, PhD, is the chief scientific officer and vice president of research at the University of Ottawa Heart Institute. She holds a University Research Chair and is the director of the Vascular Inflammation and Metabolism Laboratory. She is a full professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. She leads the Ottawa region strategic research innovation cluster on vascular inflammation and metabolism. From 2022 to 2024, Dr. Rayner was assistant dean of research in the Faculty of Medicine at the University of Ottawa.
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